The utmost suggested dose is a hundred mg and it is not suggested to choose more than one dose per day. Sildenafil could be taken with or with no food items, but having it using a higher-Unwanted fat meal may possibly boost the time prior to the medication starts Operating.If you are taking sildenafil after you try to eat a high-Body fat meal, suc

Sildenafil is a potent and selective inhibitor of cGMP-particular phosphodiesterase type 5 (PDE5), which can be to blame for degradation of cGMP inside the corpus cavernosum. The molecular framework of sildenafil is similar to that of cGMP and acts as a competitive binding agent of PDE5 from the corpus cavernosum, causing a lot more cGMP and increa